A: The small hormones from the thyroid, adrenal & reproductive organs as well as the large hormone insulin are major movers for the determination of cognitive function, the mood disorders, anxiety, panic attack, bipolarity, drug dependency, alcoholism, psychosis & migraine syndrome.  So progesterone & synthetic progestins can drive depression & fatigue, while disturbances in the adrenal hormone cortisol are at the core of the majority of mental illnesses, by regulating the cash flow between limbic cell destruction & cell renewal in a critical way.  It follows that correcting hormonal disturbances would equally have the power to cure mental illness.  

A; It has been demonstrated that estradiol therapy when applied in the right, non-erratic manner & in appropriate, adequate dosage, can prevent & effectively rein-in psychosis, as long as other hormone therapies such as potent progestins are not allowed to run interference on this wonderfully benevolent mechanism.  So the answer is an undoubted YES, & our clinical experience bears this theory out.